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H., Ghesquire, B., McVicar, D

Potential drug interactions Sermorelin has no known major drug interactions, but may have the following interactions with certain drugs: Glucocorticoids (prednisone) May blunt growth hormone (GH) release Oral estrogens May increase IGF-1 resistance Insulin or sulfonylureas May alter glycemic control Somatostatin analogs May antagonize Sermorelins effects Dopamine antagonists May disrupt human growth hormone (HGH) regulation GABAergic meds May reduce pulsatility of HGH release Beta blockers (Metoprolol or Propranolol) Other secretagogues/peptides May result in unsafe levels of HGH Other important safety information Sermorelin is only for patients who are at least 30 years old

However, much less is known about how amino acid metabolism may regulate mitochondrial dynamics

(6) neurotrophic agents offer the ability to facilitate synaptogenesis, neurogenesis and neuroprotection thus greater research attention must be directed toward creating small molecule analogs designed to penetrate the BBB and activate these brain systems