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It is believed that this high production exceeds the detoxifying ability of D2HGD leading to its intracellular accumulation even when the later enzyme is functioning normally [86]

Short-acting testosterone appears to have lesser effect on male reproductive potential compared to long-acting testosterone in mice

and progressors as those with progressive disease (PD) at an initial evaluation after 3 cycles of treatment

In fact, the direct antimicrobial activities of the proteinase inhibitors were not determined to date, but it is possible that the inhibitors could interfere with acyl-serine proteases involved in bacterial cell wall synthesis