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In this study, we found that VNS significantly mitigates GSH depletion in the myocardium of rats with hepatic I/R and increases the protein expressions of SLC7A11 and GPX4

In accordance with the guidelines outlined in the National Medical Products Administration (NMPA) Technical Guideline for Bioequivalence Studies of Generic Chemical Drugs with Pharmacokinetic Parameters as the Endpoints, and considering the characteristics of the drug used in this study, the overall design was a single-center, open-label, randomized, two-formulation, two-period, two-way crossover, fasting pharmacokinetic study

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Kawamata J, Suzuki S, Shimohama S (2012) 7 nicotinic acetylcholine receptor mediated neuroprotection in Parkinsons disease