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On September 3, 2024, Athira announced the result

Nitric oxide in the normal kidney and in patients with diabetic nephropathy

Bone marrow suppression is a significant concern with Alimta, which can lead to neutropenia (low white blood cells), thrombocytopenia (low platelets), and anemia (low red blood cells)

Nonetheless, the aforementioned animal models, although extremely useful in investigating specific molecular mechanisms in the pathogenesis of ulcerative colitis, do not truly recapitulate disease as observed in patients, as IBD is a multifactorial disease and most clearly is not caused by a single mutation or defect in cellular or molecular pathways