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The method of claim 56, wherein at least two amino acid codons in the antigen binding site are mutagenized and a set of degenerate oligonucleotides that encode all nineteen naturally-occurring amino acid variants are provided for each amino acid codon mutagenized

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She discovered that the ER maintains its oxidized equilibrium by importing from the cytosol an oxidized form of glutathione called GSSG and exporting a reduced form called GSH