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Various species of edible mushrooms are involved in the modification of the human defensive system and exhibit biological activities such as antioxidant, antimicrobial, and many other medical benefits (Table 2)

However, under certain conditions, ferritin is degraded through a selective autophagy process known as ferritinophagy, which is mediated by NCOA4

In addition, H2A.X, NeuN, and glial fibrillary acidic protein (GFAP) expression levels were analyzed to evaluate DNA damage, neuronal integrity, and glial activation, respectively.While nNOS, 8-OHdG, Caspase-3, H2A.X, NeuN, GFAP, MDA, and iNOS levels increased in the DM group, it was observed that tissue damage decreased in a dose-dependent manner in the ZO treatment groups

Tan Z, Ou Y, Cai W, Zheng Y, Li H, Mao Y, et al