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Retatrutide produces higher rates of nausea (43% vs 20-47%), diarrhea (33% vs lower), and vomiting (21% vs lower) at their respective maintenance doses

Sanders et al

European Journal of Anaesthesiology, 18 (7), 419-422

Taken together, compound 1D228 may be a promising candidate for the next generation of c-Met and TRK inhibitors for cancer treatment, and offers a novel potential treatment strategy for cancer patients with abnormal expressions of c-Met or NTRK, or simultaneous of them