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LamotheBBesseACamposADWebsterWKWuHDarnayBG.Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

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Clinical specimens exhibit marked metabolic protein dysregulation - PGC-1 expression decreases 65% compared to controls, concurrent with diminished UCP1 and Carnitine palmitoyltransferase 1 (CPT1) protein levels as determined by immunoblot analysis (88)

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