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The action of lithium in diminishing levels of free inositol and DAG holds significant therapeutic implications (Fig

For example, deferoxamine, an iron-chelating agent, is an approved treatment for iron overload

Vitamin C deficiency may increase risk for ulcers and subsequent dence to support contentions that high doses hemorrhage

Although this biotransformation can make the xenobiotic less toxic, in some cases the secondary metabolite is more toxic than the parental compound (bioactivation)