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Although this review explored multiple antioxidant-enzyme interaction strategies, some of these approaches are still undergoing trials, and their efficacy has not been fully established

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ROS also function as HIF-1 activators by both transcriptional activation and PHD activity regulation [90]

The mechanistic assembly of cholinergic system-glaucoma relation can be broadly classified into 3 domains: protection of undamaged RGCs and axons, rescue of minimally damaged RGCs and axons, and regeneration of damaged RGCs and axons (Figure 8)