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No, Lions Mane is not a stimulant like caffeine

The results were absolutely reassuring for all fans of this supplement: No changes to the hair

A., SHARE Investigators

Differentiation of the cells to myocytes was induced by incubating the cells in a standard differentiation medium consisting of DMEM with 2% horse serum (Thermo Fisher Scientific) for 6 days, and was confirmed by upregulation of mRNA expression of Myod1 and Myog (Jing et al., 2022)