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Keywords: Cuprizone, Multiple Sclerosis, Demyelination, Oligodendrocytes, Inflammation, Cell death, Astrocytes, Microglia, CNS Background Multiple Sclerosis (MS) is a chronic neurological disorder characterized by the loss of myelin or demyelination

We also thank Alicia Thompson, formerly the head of the Electron Microscopy and Microanalysis Center at USC (now retired), for taking the photographs shown in Fig

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