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Additionally, a profound decline in FBS, insulin, and HOMA-IR ( p = 0.014, 0.051, 0.024, respectively) and an increment in QUICKI ( p = 0.019) were observed in the L-carnitine + synbiotic group compared with the L-carnitine + placebo group post-intervention, which remained significant after adjustment for the baseline levels and possible confounding factors

( h ) Mice with intraperitoneal Ovcar8-CCNE1 tumors were treated with vehicle or mildronate (n = 8/group)

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Alcoholic fatty liver disease is another major cause of fatty liver disease, for which carnitine supplementation may also be beneficial for improvement (77)