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Slices were sectioned cross- and length-wise (400 ) to ensure penetrability of the drug, using a Mcllwain tissue chopper (Brinkmann, Gomshall, UK) and transferred to a gassed (95% 0 2 /5% CO 2 ) incubation chamber containing aCSF for 90 minutes at room temperature

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Our findings demonstrate that THC exerts antiinflammatory effects in a CRSinduced depression model, as indicated by reduced serum levels of IL1 and TNF