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Dosage Precautions Treatment with this drug should be administered with caution if the animal has chronic renal failure

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Muzumdar RH, et al

By binding to cardiolipin, SS-31 may help stabilize mitochondrial membranes, enhance ATP production, and reduce oxidative stress and cell death

Conventional DMARDs (e.g., methotrexate, leflunomide, sulfasalazine): Methotrexate slows joint damage and suppresses inflammation but causes hepatic toxicity and bone marrow suppression, leading to 30% treatment discontinuation within one year (8)