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However, the active form of thiamine is ThDP, which acts as a coenzyme for three important enzymes - transketolase (TKT), a key enzyme of the pentose phosphate pathway important for nucleic acid and lipid biosynthesis, pyruvate dehydrogenase complex (PDHC), an enzyme complex that converts pyruvate to acetyl-CoA and links glycolysis to the citric acid cycle, and -ketoglutarate dehydrogenase complex (OGDHC), a complex involved in the TCA cycle [30]

Sagy et al., 2024

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations

Methionine is not synthesized in the body, which means it must be ingested or supplemented