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The semen concentration was estimated by counting spermatozoa under a phase contrast microscope using a Neubauer improved/Petroff counting cell

These changes cause cellular dysfunction, cell cycle arrest and senescence with consequent secretion of pro-inflammatory and pro-fibrotic factors such as interleukin-1 (IL-1) and IL-6, TGF-1 and matrix metalloproteinases (MMPs) [12, 13]

[13] The oral tablet formulation offers advantages in terms of ease of administration and patient convenience compared to parenteral alternatives

Prenatal folic acid supplementation did NOT protect against spina bifida risk in women drinking 3+ cups of tea daily odds were 23x higher [17]