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To determine the hydrophobicity of the sequence, a PROT Scale tool based on Kyte and Doolittle hydrophobic scale was used ( Hydrophobicity indices were determined as the Grand average of Hydropathicity (GRAVY) values of hydrophobic regions using the ProtParam tool ( [34]

Kinga Krzeminska Images 3 Ana Maria Serrano Images GSHGSH 2 2 Claudia Totir Images 1 Olga Rolenko Images Daniel Grizelj Images FDA USPNSF Olena Ruban Images N-NAC - 3 CE B B12 15g translation : Mutsumi Matsunobu photo : Getty Images check Getty Images check Getty Images

While conventional antioxidants transiently neutralize extracellular/cytoplasmic ROS, they fail to address ROS overproduction from dysfunctional mitochondriathe root cause