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Although TR/GR-null livers generate some of their cysteine through the serine transsulfuration pathway, we here show that most cysteine in TR/GR-null livers comes from a pathway in which pyridoxal-phosphate-dependent cleavage of a carbonsulfur bond in cystine generates cysteine persulfide, which decomposes nonenzymatically into cysteine

Understanding those early symptoms is where science meets intuition

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10.1016/j.curtheres.2014.01.001 [DOI] [PMC free article] [PubMed] [Google Scholar] Tuba-Kartal A., ala-Mutlu Z