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There is a need to identify objective biological markers associated with diagnosis or clinical severity of the disorder

The lowest % of atretic follicles and degenerated corpora lutea was detected in the DOX+(SP + L-car) group, followed by the DOX + L-car group and then the DOX + SP group, as the histoarchitecture of the DOX+(SP + L-car) group was more or less the same as the control group

An example of damage to astrocytes and disappearance of connexin-43 normally seen in association with astrocytes is shown in Figure 12 (187)