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A recent hypothesis postulated that overexpression of 7 nAChRs in astrocytes is an early modulator of -amyloid pathology in the context of AD 1,559 (Fig

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We predicted that CHR-P participants would be characterized by reduced levels of glutamate and/or Glx in left auditory regions and increased levels of GABA in right auditory regions, consistent with the earlier findings in ScZ patients ( Materials and Methods Data were collected as part of the YouR-Study (The Youth Mental Health Risk and Resilience Study), which is a longitudinal study funded by the Medical Research Council (MRC) ( Participants Auditory cortex 1H-MRS data was included from three groups of participants: (1) participants meeting CHR-P criteria