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April 4 Product: Basilea Pharmaceutica Zevtera Indication: Staphylococcus aureus bloodstream infections and community-acquired bacterial pneumonia Fifteen years of persistence paid off for Basilea Pharmaceutica on Thursday, as the FDA approved its antibiotic Zevtera for adults with Staphylococcus aureus bloodstream infections and adult and pediatric patients three months to less than 18 years old with community-acquired bacterial pneumonia

In the SURPASS-2 trial, which compared it head-to-head against semaglutide 1 mg over 40 weeks, tirzepatide lowered HbA1c by about 2.0 to 2.3 percentage points across its 5, 10, and 15 mg doses, versus roughly 1.9 points for semaglutide, with greater weight loss as well

Consequently, these findings raise important questions regarding the extent to which the effects of GLP-1 receptor agonism and amylin receptor activation may be additive or synergistic across different metabolic phenotypes