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I do recommend checking out the interesting research compiled by Watanabe & Bito (2017) in the Sources and References list below

Digestive Upset- In some instances, B12 injections may cause mild gastrointestinal symptoms such as nausea, diarrhoea, or stomach cramps

[9] Along with his third Crichton Medal, he also won a handful of other accolades, including the AFLPA best captain award, the Lou Richards Medal and selection in the 2012 All-Australian team as the centreman

Supporting the liver's natural pathways is beneficial at any age, but it becomes increasingly important as we are exposed to more environmental stressors over time