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Compared with non-diabetic controls, diabetic mice exhibited markedly elevated renal tubular injury biomarkers KIM-1 and NGAL in both renal tissue and urine, accompanied by pronounced folding and disruption of the tubular basement membrane ( Iron is an essential element for the survival of cells ( On the basis of mass spectrometry analysis and network pharmacology research, TSWN formula may prevent DKD and decrease urinary albumin levels by AMPK pathway ( Ferroptosis regulates cell death characterized by iron-dependent lipid peroxidation (72, 73)

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Brain, Behavior, & Immunity - Health