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Insights into oxidative stress in bone tissue and novel challenges for biomaterials

Concurrently, therapy-induced NF-B activation upregulates APOBEC cytidine deaminases, which catalyze cytidine-to-uracil mutations in single-stranded DNA to fuel genomic instability [47, 48]

Nutrient supplements and dietary patterns rich in nootropic compounds for NDDs Nutrient supplementation or diets rich in nootropic compounds such as PUFAs, essential amino acids, dietary fibers, polyphenols, and other phytochemicals, hold significant potential for therapeutic intervention of NDDs and mediating brain health outcomes [29, 30]

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