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The nature and treatment of the cancer are the main factors influencing the short-term development of fat accumulation after anticancer therapy [58]

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To quantify cell loss, slides were blinded and a pathologist (K.J.E.) assessed the approximate total acellular tissue area (including abnormalities such as stroma, fat, and necrosis) in 1030 highpower fields for each sample

In the second part of the review, the current evidence of the role of impaired barrier function in the pathophysiology of selected gastrointestinal and liver diseases is discussed