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(3) modulation of the Bax/Bcl-2 balance and the caspase cascade, as well as the blockade of mitochondria-dependent apoptotic pathways

Thank you to our sponsors AG1: BetterHelp: Helix Sleep: LMNT: Function: Timestamps (00:00:00) Alex Marson (00:02:21) Diseases & Current Biological Landscape

We can also see a direct effect on oligodendrocytes, preserving their lipid metabolism, which may favor myelin homeostasis (170)

Methods Cell culture Human embryonic kidney (HEK) 293E (ATCC, CRL-1573), Raji cells (ATCC, CCL-86), WSU-NHL (DSMZ GmbH, ACC 58), DOHH-2 (DSMZ GmbH, ACC 47) and SU-DHL-4 (DSMZ GmbH, ACC 495) were maintained in RPMI 1640 medium with L-glutamine (ThermoFisher) all supplemented with 10% heat-inactivated (HI) fetal bovine serum (FCS) (Merck), 25 g/mL streptomycin and 25 U/mL penicillin (ThermoFisher)