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In order to distinguish cleavage-dependent and independent effects in SCA3 pathology, there is an urgent need for novel methodologies that enable the visualization of protein aggregates in living brains and allow effective discrimination of the triggers of nucleation, which could be achieved by developing radiotracers for positron emission tomography (PET) or similar procedure

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B12 is important in making the myelin sheath, which transmits the nerve impulses

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