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Glutathione regulates melanin production by inhibiting tyrosinase, the enzyme that triggers pigmentation

Table 3 summarizes the most commonly used treatments to reduce IRI, which include adenosine agonists, endothelin antagonists, antioxidants, complement activation inhibitors, apoptosis inhibitors, anti-inflammatory and proangiogenic, metabolic inhibitors, bioactive gases, traditional Chinese medicine, cell-based therapy, etc