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Furthermore, identifying the major pathway linking NADPH and ER function is complicated by the fact that NADPH regulates three major redox pathways: glutathione, thioredoxin, and NOX enzymes, each of which interactseither directly or indirectlywith protein folding machinery in the ER

In contrast, mucolytics and airway clearance techniques act as supportive therapies, facilitating the removal of secretions and controlling symptoms without altering the disease's trajectory

Dysfunction of the autoimmune system: The immune system actually mistreats the thyroid gland itself

doi: 10.2147/IJN.S157541 148 MahmoodiNMKarimiBMazarjiMMoghtaderiH