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While these medications have a relatively low intrinsic risk of causing dangerously low blood sugar when used alone, the risk increases significantly when combined with insulin or sulfonylureas

Direct glutathione supplementation: An RCT in India randomized 206 people with type 2 diabetes (aged 31-78, HbA1c 7.1-9.7%) to receive either 500 mg glutathione daily alongside antidiabetic medications for 6 months, or antidiabetic medications alone

Weeks 9-12 (4mg): A critical transition point

Further research is still required to explore the detailed role of HDAC1-3 in histone lactylation and neuronal excitotoxicity during epilepsy