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P., et al., Influence of Methylcobalamin on the Antineoplastic Activity of Methotrexate, Pharmaceutical Chemistry Journal 12, no

Specifically modified nanocarriers delivering targeted drugs can clear damaged mitochondria by initiating the mitochondrial autophagy program, effectively restoring mitochondrial homeostasis, reducing the neurotoxicity caused by oxidative stress, and rescuing the motor dysfunction in animal models

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If cancer is very sensitive to the damaging effects of free radicals, then it might be possible to develop drugs that target cancer cells specifically and prevent them from producing antioxidants or that ramp up free radical levels inside of the malignant cells, exploiting their newly discovered weakness.