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*Correspondence: Yi Hua, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

A 100-l aliquot of each extract was heated at 95C for 1 min and cooled in an ice bath

Therefore, whereas LU may modulate the parasite to institute resistance against MQ due to the physicochemical similarities in the two drugs, AQ may do the same through changes in Pfmdr1