glutathione parasites X-ray structure of S-transferase from the malarial parasite Plasmodium falciparum Loss of vitamin C biosynthesis

Loss of vitamin C biosynthesis protects from the pathology of a parasitic infection PNAS TWiP 279: Tolling for hookworms TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S transferase 1, an enzyme that performs a crucial enzymatic step in hookworm PfK13 associated artemisinin resistance slows drug activation and enhances antioxidant defence, which can be overcome with sulforaphane bioRxiv Unusual thiol based redox metabolism of parasitic flukes ScienceDirect

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