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Supplementing with the glutathione precursors for 24 weeks successfully reversed these metabolic defects, corrected the glucose steal, and led to significant, measurable improvements in cognition and executive function

2.3 Preparation of sperm suspensions On February 24 th , 2024, frogs were euthanised according to methods approved by the University of Wollongong s Animal Ethics Committee (see section 2.8 Ethics review statement below), and testis tissue immediately extracted, weighed, and macerated in 170L of simplified amphibian ringer (SAR: 113mM NaCl, 1mM CaCl 2 , 2mM KCl, 3.6mM NaHCO 3 )