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Gastroenterology 159, 13751389

Moreover, a direct potential way could be the inhibition of presynaptic NMDA receptors and thus the activation of postsynaptic AMPA receptors by the release of glutamate

The analgesic and anti-inflammatory effects of aspirin are due to the inhibition of cyclooxygenase 2 (COX2), specifically vascular COX2, responsible for the production of prostaglandin