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doi: 10.1093/toxsci/kfj034

They primarily play a role in allergic reactions by releasing inflammatory mediators such as histamine and heparin (125, 126)

There is no standardized clinical guidance for DILI treatment and most treatments are nonspecific

Conclusion In conclusion, this review focuses on key CICD mechanisms, including cell death pathways, necroptosis, ferroptosis, and autophagy-dependent cell death, that can achieve apoptosis-resistant cancer cell elimination