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This causes basal synaptic transmission.[ref] Rare genetic mutations in the GRIA1 gene are associated with intellectual disability and neurological disorders.[ref] Similarly, mutations that cause gain or loss of function in GRIA3 lead to neurodevelopmental disorders and seizures.[ref] Interestingly, AMPA receptors and glutamate are involved in the release of reproductive hormones from the brain, and these receptors control ovulation in women.[ref] Weak glutamate stimulation will cause the activation of AMPA receptors, while NMDA receptors require a strong stimulus

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This is why it is used as a topical hair treatment

H 2 O 2 is also generated by urate oxidation to allantoin using urate oxidase (Kurylenko et al., 2019)