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SKU: 84764408177
Price: 25.55 USD
Availability: InStock
Rating: 4.8532 (15 reviews)

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& Vaissire, B

J.O'donnellP

Non-coding RNAs as cytoprotective agents in the UV-induced stress response of melanocytes Exposure of melanocytes to UV radiation triggers a complex regulatory network involving various non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), which play crucial roles in cytoprotection against oxidative stress

E2 deficiency downregulates the Er-PGC-1-NRF1 transcriptional axis, leading to suppressed SOD2 expression and impaired clearance of mitochondrial ROS, initiating a vicious cycle of oxidative damage and mitochondrial destabilization (122)