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Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox

The concentration of polyamine spermidine was 3.5 times higher in PS-L skin compared to C (p = 0.000002) and 1.5 times higher than in PS-NL skin (p = 0.03)

12 Conversely, non-RBD-PD may reflect a brain-first subtype, in which pathological -synuclein originates within the central nervous system and then spreads peripherally