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During the preoperative phase, patients commonly undergo gastrointestinal preparation, adhere to dietary and fluid restrictions, and experience psychological stress associated with surgery, all of which can significantly impact the gut microbiota

In controlled research environments, Epithalon has been used to explore: Telomerase activation and telomere length dynamics in cell culture Oxidative stress and free-radicalrelated cellular damage Regulation of specific gene promoters related to immune function, extracellular matrix integrity, and circadian signaling Fibroblast activity, collagen and extracellular matrix maintenance in skin models Experimental tumor-growth kinetics and radiation-response pathways Melatonin synthesis and circadian-related protein expression Retinal structure and electrophysiologic function in selected ocular models All findings remain exploratory and model-dependent, and are interpreted strictly within the context of basic and translational research

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Although Isotretinoin is often called Accutane, the brand name Accutane is no longer available in the United States