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Aging is associated with declining expression of intestinal amino acid transporters, reduced gut barrier integrity, and a condition called anabolic resistance , where muscle tissue becomes progressively less responsive to amino acid stimulation

Cystine declined from 0.42 mg g -1 in the control to 0.33 mg g -1 at 300 g L -1 Pb, followed by an increase to 0.48 mg g -1 at 500 g L -1 Pb (Figure 8)