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Description

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy

Under continuous stimulation of IGF-1, IGF-1R/MAPK/PI3K signaling is activated, leading to resistance to estrogen tamoxifen and fluvestrant

"Underlying factors such as hormonal changes may not manifest until a person goes on vacation to a southern location like Florida, or during the summertime when she spends more time in the sun," says Dr