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Description

PMID 40544432

Andersen, M.A

Cagrilintide as a stand-alone drug has been studied through Phase 2, [1] but most of the headline cagrilintide numbers people cite actually come from CagriSema the fixed-dose combination of cagrilintide 2.4 mg with semaglutide 2.4 mg which advanced into the Phase 3 REDEFINE program

These experiments confirmed that cagrilintide is a potent dual agonist, activating both receptor types, which is crucial for its therapeutic effect on reducing food intake and body weight, as demonstrated in preclinical rat models