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In this regard, E2 rapidly increased lactate production in human MCF-7 breast cancer cells in a PI3K/AKT-dependent mechanism that was speculated to be initiated by a membrane-bound pool of ER (201)

Neuropediatrics 44:218221 Celestino-Soper PB, Violante S, Crawford EL, Luo R, Lionel AC, Delaby E, Cai G, Sadikovic B, Lee K, Lo C, Gao K, Person RE, Moss TJ, German JR, Huang N, Shinawi M, Treadwell-Deering D, Szatmari P, Roberts W, Fernandez B, Schroer RJ, Stevenson RE, Buxbaum JD, Betancur C, Scherer SW, Sanders SJ, Geschwind DH, Sutcliffe JS, Hurles ME, Wanders RJ, Shaw CA, Leal SM, Cook EH Jr, Goin-Kochel RP, Vaz FM, Beaudet AL (2012) A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism

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