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At the same time, the higher concentration of LPS in the serum might promote the inflammation in the colon of mice from the EpCAM +/ + DSS group through TLR4-ER stress-p38 pathway

There are more triggers for pigment production than there are pathways for its elimination

Because treatment interruptions and non-adherence are common, failing to recognize these biologically driven rebound risks can mislead research, guidelines, and clinical decisions

A recent finding shows that cells lacking ATAD1, an AAA + ATPase that removes substrate proteins directly from the OMM for degradation, are hypersensitive to proteasomal inhibition (Winter et al., 2022)