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doi: 10.1038/NATURE23007 93 FangKXuZJiangSYanCTangDHuangY

The glycan sugar component (galactose, fucose, and mannose) of sIgA contributes to sIgA resistance to proteolysis in the intestine and functions through a broad spectrum of binding of pathogenic bacteria when compared with the antigen specific binding of the variable region of the Ig structure