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This analysis confirmed that NKX2-1 expressing cells synthesize more de novo serine and glycine (M+2/M+3) starting from glucose compared to control cells (Figure 3)

Accordingly, in vitro treatment of macrophages with carbon-monoxide releasing molecules (CORMs) enhances STAT3/STAT6 activation to induce their anti-inflammatory phenotype ( in vivo A549 lung carcinoma model, Nemeth et al