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J Thorac Cardiovasc Surg 167(4):1444-1453.e4, 2024

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Methylation of gene promoters such as CADM1 , CCNA1 , CDH1 , DAPK1 , FHIT , MAL , P16 , PAX1 , RAR- , and RASSF1 can be considered as non-invasive biomarkers for early cervical lesions ( CADM1 methylation and D-dimer testing is a biomarker that can be used for early screening of CC (Rong et al., 2019)

And then you experience this anxiety and shakiness, jitteriness, fatigue as a consequence of sort of these exaggerated concentrations of stress hormones