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For example, TLR1, TLR2, TLR4, TLR5, TLR6, TLR10 are indeed located on the plasma membrane, whereas TLR3, TLR7, TLR8, TLR9, and TLR11 families are intracellular TLRs expressed in the membranes of endosomes and lysosomes (Lester and Li, 2014)

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